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Glucophage is an oral diabetes medicine used to treat type 2 of diabetes. Its active substance is Metformin which belongs to biguanide class of substances. It reduces concentration of glucose in blood suppressing metabolism of glucose in the liver, reducing absorption of glucose from the gastrointestinal tract, and enhancing its utilization in tissues. Glucophage stabilizes or reduces body weight. The therapeutic effect is not observed in the absence of insulin in the blood. It does not cause hypoglycemic reactions. It improves fibrinolytic properties of blood. It I used to treat diabetes mellitus (type 2) in adults also in patients for who treatment with sulfonylurea was ineffective, especially in cases followed by obesity.
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Hypersensitivity, hyperglycemic coma, ketoacidosis, kidney failure, liver disease, heart failure, acute myocardial infarction, respiratory failure, dehydration, infectious diseases, extensive surgery and trauma, alcoholism, reduced-calorie diet (less than 1000 kcal / day), lactic acidosis (including history), pregnancy, breastfeeding. The drug is not prescribed to take 2 days before a surgery, radioisotope and X-ray examinations, CAT scanning (CT). Glucophage is contraindicated in patients over 60 y.o., or doing hard physical work (risk of lactic acidosis increases).
Glucophage is an oral diabetes medicine used to treat type 2 of diabetes. Its active substance is Metformin which belongs to biguanide class of substances. It reduces concentration of glucose in blood suppressing metabolism of glucose in the liver, reducing absorption of glucose from the gastrointestinal tract, and enhancing its utilization in tissues. Glucophage stabilizes or reduces body weight. The therapeutic effect is not observed in the absence of insulin in the blood. It does not cause hypoglycemic reactions. It improves fibrinolytic properties of blood. It I used to treat diabetes mellitus (type 2) in adults also in patients for who treatment with sulfonylurea was ineffective, especially in cases followed by obesity.
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