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Symptoms of overdose may include drowsiness, disorientation, extrapyramidal disorder (especially in children). If you think that took too much of Motilium and experience symptoms listed above contact your doctor immediately, you may need a medical help.
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Take Motilium orally 30 minutes before a meal. In adults and children older than 5 y.o. take 10 mg 3-4 times a day when dispepsia is diagnosed. In patients with severe nausea and vomiting Motilium daily dose is 20 mg 3-4 times a day. In patients with kidney failure correction of the dose is necessary, number of daily intakes should not exceed 1-2 times. This is only general recommendations and for each individual case consult your doctor as different conditions require different correction of the dose.
Cimetidine and sodium bicarbonate reduce effects of Domperidone. Anticholinergic medications neutralize effect of Motilium. Blood levels of Motilium are increased by azole antifungal agents, macrolide antibiotics, HIV protease inhibitors, nefazodone (antidepressant). Motilium is compatible with antipsychotic (neuroleptics) medications, dopamine receptor agonists (bromocriptine, L-dopa). Simultaneous treatment with paracetamol and digoxin had no effect on the concentration of these medications in the blood.
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