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Baclofen may interact with next medicines and products such as alcohol, antihistamines, medicines for depression, anxiety, and other mental conditions, medicines for pain like codeine, oxycodone, tramadol, and propoxyphene, medicines for sleep, phenobarbital. Use of Baclofen with other drugs may lead to additional reduction in brain function. For example, the use of Baclofen and tricyclic antidepressants together may cause muscle weakness; the use of Baclofen and monoamine oxidase inhibitors can result in greater depression of brain function as well as low blood pressure.
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