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Individual hypersensitivity, arterial hypotension, cardiogenic shock, pregnancy, breastfeeding. Cautiousness is important when Norvasc is administered in patients with chronic heart failure diabetes, lipid metabolism disorders, liver failure and to persons younger 18 y.o.
This medication belongs to the group of calcium channel blockers. Norvasc selectively blocks channels of L-type (one of six types of channels in tissues) located in a vascular wall, myocard and in particular in cells of conducting and contractile systems of myocardium. By blocking Ca+ ions transfer through membrane Norvasc decreases tone of vessels, arterial pressure. The medication is used to treat hypertension, ischemic heart disease, angina.
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